All pimples form the same way, but they have different characteristics and shapes. They also can behave differently on different people. Acne occurs when a hair follicle becomes clogged and inflamed. This forms what's called a comedo. As the follicle continues becoming even more clogged, the comedo becomes engorged and inflamed, and forms a pimple. There are several types of acne, and each requires a different treatment.
The best time is after a hot shower. When I say hot, I don't mean scorching hot. Body temperature water heat will do just fine. The skin tends to be more supple and it is easier to squeeze your pimples with clogged pores wide open.
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